Drug Database
BE

bexarotene (Targretin Gel)

✓ Approved

Eisai Co., Ltd. · RXRA · Small Molecule

What is bexarotene?

bexarotene is a small molecule developed by Eisai Co., Ltd.. It is approved for therapeutic indications via topical.

Drug Profile

Brand NamesTargretin Gel
CompanyEisai Co., Ltd.
Drug ClassSmall Molecule
Molecular TargetRXRA, RXRB, RXRG
RouteTopical
StatusApproved
Sources: ClinicalTrials.gov, Eisai Co., Ltd.

Mechanism of Action

Molecular Targets

bexarotene acts on 3 molecular targets:

RXRAretinoid X receptor alpha (RXR-alpha, RXRalpha)
RXRBretinoid X receptor beta (DAUDI6, H-2RIIBP)
RXRGretinoid X receptor gamma (RXR-gamma, RXRC)
Want deeper analysis?Noah AI can explain complex mechanisms and compare to similar drugs.

Therapeutic Indications

bexarotene is developed for 1 unique indication across 1 therapeutic area.

Therapeutic AreaConditionPhase
Neoplasms benign, malignant and unspecified (incl cysts and polyps)Cutaneous T-cell lymphoma✓ Approved

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