Drug Database
TE

teriparatide (Xinfutai Pro)

✓ Approved

Shenzhen Salubris Pharmaceuticals Co., Ltd. · PTH1R · Recombinant Proteins

What is teriparatide?

teriparatide is a recombinant proteins developed by Shenzhen Salubris Pharmaceuticals Co., Ltd.. It is approved for therapeutic indications via injectable (others).

Drug Profile

Brand NamesXinfutai Pro
CompanyShenzhen Salubris Pharmaceuticals Co., Ltd.
Drug ClassRecombinant Proteins
Molecular TargetPTH1R
RouteInjectable (Others)
StatusApproved

Mechanism of Action

Molecular Targets

teriparatide acts on 1 molecular target:

PTH1Rparathyroid hormone 1 receptor (PTHR, EKNS)
Want deeper analysis?Noah AI can explain complex mechanisms and compare to similar drugs.

Therapeutic Indications

teriparatide is developed for 1 unique indication across 1 therapeutic area.

Therapeutic AreaConditionPhase
Musculoskeletal and connective tissue disordersOsteoporosis✓ Approved

Related Research Articles

PubMedHealthcare quarterly (Toronto, Ont.)2026-08-30

Addressing Canada's Pharmaceutical Research and Development Intensity Gap: The Role of Health Data Transformation.

Mullie Thomas T, Chuck Anderson A

The life sciences industry, and specifically the pharmaceutical sub-sector, is a major funder of private sector research and development. Canada's life sciences industry reinvests less of its revenues in research and development (R&D) activities than those in peer countries, which hinders innovation, creates supply risks and contributes to Canada's poor productivity growth. Traditional approaches to incentivizing reinvestment, including tax incentives, direct funding and public research spending, have failed. As an alternative, transforming Canada's health data systems would enable faster and more comprehensive secondary use, making R&D investments safer and more productive. Our peers are already pursuing this strategy, meaning Canada risks being left behind unless we act.

PubMedExploratory research in clinical and social pharmacy2026-08-30

In defence of the drug, two hearts, one profession: Reintegrating medicines expertise and patient-centred care in pharmacy's professional identity.

Davies Neal M NM

For more than three decades, pharmacy has narrated its evolution as a movement away from the product and toward the patient. The pharmaceutical care era ushered in by Hepler and Strand in 1990 framed dispensing and product expertise as a chrysalis the profession needed to shed in order to mature. That framing has been useful, but it has also been misread, and the misreading has now been institutionalised. Some accreditation councils, regulatory and licensing bodies, and advocacy bodies have positioned the profession as one moving away from a so-called "product centric" past. The thesis of this commentary is otherwise. Pharmacy has never had a single heart; it has always had two, one beating for the drug and the other for the patient, and they have always beaten in the same chest, for four centuries and more. The pharmacist's claim to a place at the patient's bedside rests entirely on what the pharmacist knows about the molecule: medicinal chemistry, pharmaceutics, compounding, biopharmaceutics, pharmacokinetics, pharmacogenomics, radiopharmacy, pharmacognosy and now pharmaceutical artificial intelligence. The argument here is not nostalgic but expansive. Embrace them all. Without the drug, the diagnosis is a verdict, not a treatment; and without the pharmacist, no drug appears.

PubMedSoft matter2026-08-30

Bottom-up coarse-grained simulations of electric-field-induced biaxiality and switching dynamics in liquid crystals of board-like molecules.

Díaz-Acosta Adrián A, Gil-Villegas Alejandro A, Patti Alessandro A

Electric fields can alter the orientational symmetry of liquid crystals, driving the emergence of biaxial order with potential relevance for next-generation electro-optical devices. Here, we present a coarse-grained (CG) model for a liquid crystal of board-like mesogens that enables a direct connection with our previous atomistic molecular dynamics simulations. The model is constructed through a particle-based mapping scheme that preserves the intrinsic anisotropy of the molecular core while enabling access to larger system sizes and longer time scales. Effective bonded and non-bonded interactions are obtained within a bottom-up force-matching framework and validated against atomistic reference data through structural and orientational correlations. A comparison with the atomistic reference allows us to assess both the capabilities and the limitations of the present CG representation, particularly in relation to the subtle balance between nematic and weak smectic-A organisation. Building on this framework, we then investigate the response of the system to externally applied electric fields. The model successfully captures field-induced reorientation dynamics and reveals a strong dependence of the ordering kinetics on field strength. Stronger fields substantially accelerate the evolution towards equilibrium, eventually leading to a rapid-alignment regime at high field strengths. After the field is removed, the system retains residual orientational memory rather than fully relaxing to its initial disordered state, suggesting persistent field-induced correlations that may affect subsequent switching processes. Most importantly, the external field promotes the formation of a biaxial nematic phase, highlighting the ability of the model to capture subtle symmetry-breaking phenomena induced under non-equilibrium conditions and relevant to electro-optical applications. The present CG model provides an efficient and physically consistent framework for exploring equilibrium structures, switching dynamics, and field-driven non-ordering in liquid-crystalline materials.

PubMedChemical communications (Cambridge, England)2026-08-30

Cation-regulated proton conduction in node-anchored ionic-liquid/MOF-808 conductors.

Hong Yanlin Y, Wang Cong C, Li Shantao S, Jin Jincheng J et al.

Node-anchored protic ionic liquids were immobilized in MOF-808 through Zr-node post-modification to construct stable proton-conducting pathways. Cationic sulfonic acid groups strengthen hydrogen-bond networks and promote Grotthuss-type proton transport. PSO3MImH2PO4@MOF-808 achieved 3.19 × 10-3 S cm-1 at 80 °C and 95% RH with excellent stability.

PubMedAdvances in colloid and interface science2026-08-30

Characterization of solids and surface modifications by surfactants and polymers.

Rosenholm Jarl B JB

Probe molecules are used to characterize Lewis-type and Brϕnsted-type surface sites of solids. The number and strength of surface sites are determined by Langmuir adsorption isotherms and by acid-base titrations. The appearance of charged surface sites is determined by dissolution experiments and the overall surface energy by immersion experiments. First-order standard thermodynamic properties (Gibbs energies, enthalpies and entropies) are used to characterize the state of probe molecules in solution and the interaction between probe molecules and surface sites. The state of surfactants in solution is characterized using regular solution model. The adsorption to surface sites is quantified by Langmuir isotherms. Their self-assembly at surface sites is initiated at somewhat lower concentration as compared to micelle formation in solution. Loosely bound surfactants and (hemi)micelles follow the prediction of Henry adsorption isotherm. Solution properties of polymers are evaluated by applying total (Scatchard-Hildebrand, Flory-Huggins) combinatory energy. A diminished solubility results in adsorption. Polymer adsorption can be characterized using Freudlich adsorption isotherm and predicted using solubility spheres. The observations are discussed in terms of preferential solid-adsorbent (probe, surfactant, polymer), adsorbent-liquid (solubility) or solid-liquid (wetting) interactions.

PubMedJournal of chromatography. A2026-08-30

Automated miniaturized LLE-GC-MS/MS for the analysis of EPA 8270 SVOCs and multi-class pesticides in water using ethyl acetate.

Feo Maria Luisa ML, Benedetti Paolo P, Zanaboni Moira M, Tofful Luca L et al.

The determination of trace-level semi-volatile organic compounds (SVOCs) following EPA Method 8270 traditionally relies on manual liquid-liquid extraction (LLE) using large volumes of dichloromethane (DCM). However, recent 2024 TSCA regulations restricting DCM due to human health risks necessitate sustainable analytical alternatives. This study presents a fully automated, miniaturized LLE (micro-LLE) method for 170 analytes including EPA 8270 targets and multi-class pesticides (organochlorine (OCPs), organophosphorus (OPPs) and organonitrogen (ONPs) pesticides and pyrethroids). The workflow utilizes a TriPlus RSH SMART autosampler to integrate standard preparation, surrogate spiking, and extraction with on-line GC-MS/MS injection. Ethyl acetate was validated as a "green" alternative to DCM, with a 1:1 NaCl:MgSO₄ salt mixture optimizing the salting-out effect. This procedure achieved a tenfold enrichment factor using only 1.5 mL of solvent for 10 mL of sample. Method validation showed excellent linearity (R2> 0.995 for 70% of analytes) and precision (RSD < 15%). Method limits of quantification (MLOQs) between 0.05 and 10 µg/L meet stringent regulatory requirements. The method's robustness was confirmed through real-world Saharan deposition samples, identifying high levels of Phenothrin (211 ppb) and Endosulfan ether (140 ppb). This robotic workflow provides a high-throughput, sustainable solution for modern environmental monitoring.

+9996 more articles available with a free account

Sign up free to view all articles →

Ask about teriparatide