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influenza vaccine (BLB750 / Vepacel)

✓ Approved

Baxter International, Inc. · Vaccine · Vaccine

What is influenza vaccine?

influenza vaccine is a vaccine developed by Baxter International, Inc.. It is approved for therapeutic indications via injectable (others) or intramuscular (im) injection or subcutaneous injection.

Drug Profile

Brand NamesBLB750, Vepacel
CompanyBaxter International, Inc.
Drug ClassVaccine, Large Molecules
RouteInjectable (Others), Intramuscular (IM) Injection, Subcutaneous Injection
StatusApproved
Sources: ClinicalTrials.gov, Baxter International, Inc.

Related Research Articles

PubMedMicrobiology resource announcements2026-10-16

Whole genome sequences of highly pathogenic H5N1 avian influenza viruses detected in felines in Bangladesh.

Hayat Sajedul S, Badhy Shukes Chandra SC, Hossain Mohammad Enayet ME, Kundu Ashis Kumar AK et al.

Whole-genome sequences of three highly pathogenic H5N1 avian influenza viruses detected in cats in Bangladesh during 2025-2026 are reported. Phylogenetically, two strains grouped within clade 2.3.2.1a, and the other within the clade 2.3.4.4b. The isolates harbored mutations in key polymerase and HA markers associated with mammalian adaptation and virulence.

PMID 42885913
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PubMedChemical biology & drug design2026-10-16

DNAzymes and Oligodeoxyribonucleotides Immobilized on Aminopropylsilanol and Polylysine-Anatase Nanoparticles as Active Agents Against Influenza A/H5N1 Virus.

Repkova Marina M, Levina Asya A, Filippova Ekaterina E, Makarevich Elena E et al.

The nanocomposites based on aminopropylsilanol (Si~NH2) and polylysine-anatase (Ans/PL) nanoparticles bearing DNAzymes (Dz) and oligodeoxyribonucleotides (ON) can effectively inhibit the replication of the influenza A/H5N1 virus in cell culture. Nanocomposites based on both types of nanoparticles exhibit high activity. The Dz-containing nanocomposites exhibited higher antiviral activity than those containing ON, reducing influenza A/H5N1 virus production by 3.5 log versus 2.4-3.0 log, respectively. Notably, the effect of Dz incorporated into the nanoparticles was an order of magnitude higher than that of unbound Dz transfected with lipofectamine. Nanocomposites carrying control DNA fragments that are not specific to the influenza A virus genome have practically no antiviral activity, indicating the specificity of the proposed nanocomposites. It was demonstrated that the antiviral efficacy of the nanocomposites is primarily determined by the activity of DNA delivered into cells, which can be varied by altering either the nanocomposite concentration or its capacity for DNA fragments. All of the proposed nanocomposites can be considered as potential antiviral drugs.

PMID 42885400
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PubMedAmerican family physician2026-10-16

Influenza: Prevention, Diagnosis, and Treatment.

Sur Denise K C DKC, Khoo Catherine Peony CP

Influenza is typically a self-limiting viral infection that causes symptoms such as fever, chills, cough, rhinitis, headache, sweats, myalgias, and malaise. However, serious illness and complications (eg, pneumonia, death) can occur, particularly in individuals with risk factors. Annual influenza vaccination is recommended for people 6 months and older, including pregnant individuals, who do not have a contraindication to the vaccine. Rapid diagnosis of influenza using point-of-care testing in select patients increases antiviral prescribing and decreases antibiotic prescribing in those with a positive result. However, a negative rapid test result does not exclude influenza. Although most patients do not require treatment for influenza, antivirals should be initiated as soon as possible for patients who are hospitalized, have severe or progressive illness, or are at high risk of complications. Treatment can be considered in symptomatic patients who are household contacts of individuals at high risk of complications or in symptomatic health care professionals who care for patients at risk. Postexposure chemoprophylaxis with antiviral therapies can be considered in individuals who are at risk for influenza complications. Oseltamivir and baloxavir marboxil are commonly recommended antiviral treatment options for influenza. Antiviral treatment is most effective if taken within 24 to 36 hours of symptom onset and reduces symptoms by approximately 20 hours. However, there is little to no evidence that it reduces complications of influenza.

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PubMedMilitary medicine2026-10-16

The Case for Dedicated Vaccine Communication Training: A Survey of Military Pediatricians.

Auvil Daley D, Jones Katherine K, Ratusnik Rebecca R, Adams Daniel J DJ

Vaccine uncertainty is rising among families in the United States, even among military families. The ACGME mandates that pediatric residents be trained in effective communication strategies for patients and families hesitant about recommended vaccinations, yet few validated curriculum tools exist. We aimed to understand the current landscape of vaccine uncertainty experienced by military general pediatricians and see what communication strategies were routinely being implemented in clinical practice. In March 2025, 45 graduates of a mid-sized military pediatrics residency program from the years 2016-2024 who were currently practicing general pediatricians were invited to participate in a survey on vaccine communication in clinical practice. The survey was a mix of quantitative questions asking for experienced trends in vaccine uncertainty as well as open-ended questions about communication strategies being implemented. Three clinical researchers performed a manual thematic analysis of free-text answers to understand and quantify common themes. Thirty-seven general pediatricians (82%) responded, and 95% of those surveyed rated a curriculum during medical training on vaccine communication as "very" or "extremely important." Only 19% of physicians were able to recall formal training in addressing vaccine hesitancy during medical school, and only 62% during residency. The 3 most commonly declined vaccines were COVID-19, influenza, and HPV. Pediatricians reported using communication strategies focused on knowledge-sharing (65%), partnership with families (62%), and normalizing vaccines (40%). Common barriers to vaccine acceptance were mistrust and disinterest, most commonly with unwillingness to engage in a conversation. Most practicing military pediatricians who graduated from our residency program report a rise in vaccine uncertainty in their practice and agree that a residency curriculum on vaccine communication is highly important. Such curricula should encourage evidence-based communication styles using vaccine normalization while de-emphasizing the urge to combat misinformation using knowledge-sharing and should specifically address the most commonly declined immunizations.

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PubMedWorld journal of pediatrics : WJP2026-10-16

Associations between parental generative artificial intelligence health-advice use and child vaccination uptake in Japan: an exploratory cross-sectional study.

Imanishi Yousuke Y, Iorini Maria M, Jwa Sinchul S, Sakamoto Masahiko M et al.

Parents increasingly use generative artificial intelligence (AI) for health information, but evidence on parental AI use and childhood vaccination is limited. We examined exploratory associations between regular parental AI health-advice use and childhood vaccination in Japan. This cross-sectional study analyzed 2025 nationwide survey data from children aged 1 to 17 years and parents, with a linked 2023-2025 sub-analysis. The exposure was regular parental use of generative AI for health advice at least a few times per month. Outcomes were age-appropriate measles-rubella (MR) vaccination and any mumps, influenza, or coronavirus disease 2019 (COVID-19) vaccination. Modified Poisson regression estimated adjusted prevalence ratios (aPRs) and 95% confidence interval (95% CI) with parent-level clustering and covariates. Among 8282 children and 5170 parents, 1278 (15.4%) had regular AI health-advice users as parents. AI use was not associated with age-appropriate MR vaccination (aPR 1.02; 95% CI 0.97-1.09), but was associated with three vaccines. The adjusted rates were 76.6 versus 72.7% (aPR 1.05, 95% CI 1.01-1.10) for mumps, 56.7% versus 49.0% (aPR 1.16, 95% CI 1.08-1.24) for influenza, 40.6% versus 30.9% (aPR 1.31, 95% CI 1.19-1.45) for COVID-19. The COVID-19 association was strongest among parents younger than 30 years (aPR 2.58; 95% CI 1.90-3.50; P for interaction < 0.001). In the linked sub-analysis, these associations persisted after adjustment for an available 2023 household-level prior vaccination marker and attitudes. Regular parental use of generative AI for health advice was associated with mumps, influenza, and COVID-19 vaccination, but not with age-appropriate MR vaccination. These exploratory, cross-sectional findings are observational associations. They may reflect digital health engagement, health information seeking, socioeconomic differences, or favorable attitudes, rather than vaccine-specific AI advice.

PMID 42881346
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PubMedBMC public health2026-10-16

Enhancing knowledge on influenza and other pandemic threats for healthcare personnel readiness in Thailand, 2007-2024.

Sawanpanyalert Narumol N, Praphasiri Prabda P, Ditsungnoen Darunee D, Tantilipikara Peangpim P et al.

Healthcare personnel are often the first line of defense against emerging diseases. Enhancing knowledge on influenza for healthcare personnel is part of Thailand's influenza pandemic preparedness plan. Beginning in 2007, the Thailand Department of Medical Services organized trainings for Thai healthcare personnel in Bangkok and all regions of Thailand on prevention, diagnosis, treatment, and control of human seasonal, avian, and pandemic influenza. The curriculum included overviews on the global situation, clinical features and treatment, influenza epidemiology and burden in Thailand, influenza as a cause of pneumonia, laboratory diagnostics, impact of influenza in high-risk populations and increased risk for complications; influenza economic evaluation of seasonal influenza vaccination in Thailand, and immunization and planning for human influenza outbreaks. Topics initially focused on seasonal and pandemic influenza and expanded in scope to incorporate other pandemic threats, such as MERS-CoV and COVID-19. From August 2007 through December 2024, 114 trainings were conducted. A total of 26,422 attendees (range 10-700 per training) were trained, including clinicians, nurses, pharmacists, laboratory technicians, and public health scientists (professionals trained in epidemiology, disease surveillance, and health data analysis) from public and private hospitals from national, regional, provincial, and district levels in Bangkok and 41 provinces nationwide. During training sessions, participants reported that the program increased their readiness and self-reported confidence to respond to potential respiratory outbreaks. These capacity-building efforts contributed to a health workforce that was better positioned to respond to emerging respiratory threats, including the first wave of COVID-19. Educating healthcare personnel about prevention, diagnosis, treatment, and control of influenza is an important component of pandemic preparedness. Refresher courses or online tutorials may be needed periodically to maintain current knowledge.

PMID 42881450
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