Director of NIH's National Human Genome Research Institute Departs Amid Federal Restructuring

In a surprising turn of events, Dr. Eric Green, the long-standing director of the National Human Genome Research Institute (NHGRI), has left his position after more than 15 years of service. This departure comes amidst significant restructuring and layoffs within federal health agencies under the Trump administration.

Sudden Exit Raises Questions

Dr. Green's exit was reported by Stat, based on information from two NHGRI employees and internal communications. The circumstances surrounding his departure remain unclear, with journalist Sam Stein suggesting on social media that Dr. Green was fired. The National Institutes of Health (NIH) has declined to comment on the matter, stating, "We do not comment on personnel issues."

The timing of Dr. Green's departure is particularly noteworthy, as his five-year term as NHGRI head was up for renewal. According to Stat, the NIH had submitted paperwork to the Department of Health and Human Services (HHS) to renew Green's term, but it appears the renewal was not approved.

A Legacy of Genomic Advancements

Dr. Green's tenure at the NIH spans nearly three decades, beginning in 1996. He assumed the role of NHGRI director in late 2009, guiding the institute's efforts to enhance our understanding of human genetics and develop treatments for genetic diseases.

Prior to his directorship, Dr. Green made significant contributions to the Human Genome Project. His research team also uncovered genetic causes for several diseases, including Pendred syndrome, a rare disorder that can lead to hearing loss.

Broader Context of NIH Leadership Changes

Dr. Green's departure is part of a larger trend of leadership changes at the NIH. In recent weeks, several other high-profile NIH leaders have left their positions:

• Dr. Francis Collins, former NIH director and Green's predecessor at NHGRI, ended his 32-year career with the agency in late February.
• Dr. Michael Lauer, the NIH's deputy director for extramural research, left in February after nearly a decade of service.
• Dr. Larry Tabak, the NIH's principal deputy director, retired around the same time.

These departures occur against the backdrop of mass federal layoffs and restructuring under President Donald Trump's administration, raising concerns about the future direction and stability of the nation's premier biomedical research agency.