Bristol Myers Squibb Expands Cost-Cutting Measures, Eyes Future Growth Amid Patent Cliff Concerns

Bristol Myers Squibb (BMS) has announced a significant expansion of its cost-cutting initiatives, aiming to save an additional $2 billion through 2027. This move comes as the pharmaceutical giant prepares for the loss of exclusivity on two of its blockbuster drugs, Eliquis and Opdivo, in 2028.
Intensified Cost-Cutting Efforts
The New York-based company revealed in its fourth quarter earnings release that it will implement further changes to its organizational design and enhance operational efficiency. This new savings target is on top of an ongoing program that had already aimed to cut $1.5 billion in costs by the end of 2025.
CEO Chris Boerner, who took the helm in 2023, explained the rationale behind the expanded cost-cutting measures: "We cataloged a number of opportunities for us to become a more agile company, to become more nimble and speedy in terms of how we operate and given where we are on that program, as well as where we are with respect to [loss of exclusivity], we think it makes sense for us to capitalize on those opportunities now."
The company's CFO, David Elkins, reported that the original cost savings program has already realized $1.1 billion in savings to date, with $400 million still to go. "We have entered 2025 with a stronger foundation to deliver on our long-term growth strategy," Elkins stated.
Focus on Growth Products and Strategic Acquisitions
Despite the looming patent cliff, BMS is actively pursuing growth opportunities. The company is placing significant emphasis on newly approved products such as Cobenfy, which received FDA approval for schizophrenia in September 2024. BMS acquired Cobenfy through its $14 billion purchase of Karuna Therapeutics in late 2023 and is planning three Phase III trials to further develop the asset.
Boerner highlighted the company's approach to business development, citing the Karuna acquisition as a model for future deals. "We're really focused on strengthening our position in the core therapeutic areas that we have today," he said. "We need to like the science and feel that we're the rightful owners of it. The financials have to make sense."
The CEO also stressed the importance of swift due diligence and alignment between senior leadership and acquisition targets. "The senior leadership team of the company owned the decision to move forward with that acquisition," Boerner noted, emphasizing the careful consideration given to shareholder interests.
Financial Performance and Outlook
BMS reported strong financial results for the fourth quarter of 2024, with revenue reaching $12.3 billion, an 8% increase year-over-year and surpassing analyst estimates. The company's full-year revenue for 2024 rose 7% to $48.3 billion.
Looking ahead to 2025, BMS expects revenue to be around $45.5 billion, with non-GAAP earnings per share projected between $6.55 and $6.85. The company's revenue growth was attributed to strong performance across its portfolio, including both legacy products like Eliquis and Revlimid, and growth products such as Opdivo, Yervoy, and Reblozyl.
As Bristol Myers Squibb navigates the challenges of patent expirations and industry competition, its strategy of aggressive cost-cutting, coupled with strategic investments in promising therapies and acquisitions, demonstrates a proactive approach to maintaining its position as a leader in the pharmaceutical sector.
References
- BMS Adds $2B to Cost Cutting Plans, Eyes Deals After Cobenfy Success
Bristol Myers Squibb will make even deeper cuts to its organization to enhance efficiencies as it faces the 2028 loss of exclusivity for its blockbuster drugs Eliquis and Opdivo.
Explore Further
What are the potential impacts on Bristol Myers Squibb's portfolio once Eliquis and Opdivo lose exclusivity in 2028?
How does Bristol Myers Squibb's acquisition of Karuna Therapeutics compare to other recent strategic acquisitions in the pharma sector?
What are the expected growth projections for Cobenfy following its FDA approval for schizophrenia?
What is the competitive landscape like for BMS's growth products such as Opdivo, Yervoy, and Reblozyl?
What specific steps is Bristol Myers Squibb taking to enhance operational efficiency as part of their cost-cutting measures?