Ottimo Pharma Launches with Former Seagen CEO, Promising Cancer Drug Jankistomig

Ottimo Pharma has emerged from stealth with a strategic focus on innovative cancer therapies, led by former Seagen CEO David Epstein[1]. The company is dedicated to advancing Jankistomig, a PD1-VEGFR2 bifunctional antibody designed to enhance cancer treatment by targeting immune checkpoint inhibition and angiogenesis[1][2]. This promising candidate is positioned as a potential competitor to widely used immunotherapies like Keytruda, with an expected IND filing in 2025[1]. Backed by Medicxi, and assembled with industry veterans like Mehdi Shahidi and James Sabry, Ottimo aims to revolutionize cancer immunotherapy through its novel targeting mechanisms[2].
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What specific challenges does Jankistomig aim to overcome in comparison to existing treatments like Keytruda?
How does the dual-targeted approach of Jankistomig differ from other PD-1 inhibitors in the market?
What are the expected advantages of Ottimo Pharma's bifunctional antibody technology in cancer treatment?
How has David Epstein's experience with Novartis and Seagen influenced the strategic direction of Ottimo Pharma?
What role does Medicxi's backing play in Ottimo Pharma's development and future plans for Jankistomig?