Probe Into Novo's Ozempic and Possible Eye Disorder Risk Intensifies After Studies

The potential link between Novo Nordisk's Ozempic and a rare eye disorder, non-arteritic anterior ischemic optic neuropathy (NAION), has gained attention following recent studies from the University of Southern Denmark and other researchers. These studies suggest a slight increase in the risk of NAION among users of Ozempic, which contains the active ingredient semaglutide, although the absolute risk remains low[1][2]. NAION, characterized by impaired blood flow to the optic nerve leading to sudden vision loss, predominantly affects individuals over 50[1]. The Danish Medicines Agency has flagged this potential risk and has sought a review by European Pharmacovigilance Risk Assessment Committee, although Novo Nordisk maintains their stance on the favorable benefit-risk profile of semaglutide[2].
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What measures will Novo Nordisk take if the European review confirms a significant risk between Ozempic and NAION?
How does the potential risk of NAION impact the current prescription guidelines for Ozempic?
What alternative treatments are available for patients concerned about the risk of NAION with Ozempic usage?
How do the findings of the recent Danish studies compare with previous global research on semaglutide's side effects?
What are the long-term implications for Novo Nordisk if a causal link between Ozempic and NAION is established?