Upstream Bio and CAMP4 Therapeutics Venture Into Nasdaq with Notable IPOs for Inflammatory and RNA Drug Development

Upstream Bio has successfully raised $255 million through its initial public offering (IPO) by issuing 15 million shares at $17 each, surpassing its initial goal of $182 million[1][2]. The IPO, listed under the ticker UPB, will fund the advancement of its lead program, verekitug (UPB-101), which targets thymic stromal lymphopoietin (TSLP) and is in Phase II trials for severe asthma and chronic rhinosinusitis with nasal polyps[1][2]. Additionally, the company has plans for future studies in chronic obstructive pulmonary disease (COPD)[1][2].
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